Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059430 | 0.86 | HCAR3 (0.42) | KCNH2HCAR3CNR1HTT | |
| SCHEMBL28320614 | 0.84 | GPR84 (0.41) | KCNH2CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL1799729 | 0.78 | GBA1 (0.39) | LMNAELANECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11242253 | 0.70 | DNM1 (0.31) | LMNADNM1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL3226743 | 0.70 | KCNH2 (0.49) | LMNAKCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9812726 | 0.69 | KCNH2 (0.47) | LMNAKCNH2CYP1A2CYP3A4CYP2D6 | |
| Dodecane SCHEMBL28106124 | 0.68 | HTT (0.36) | KCNH2CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL9278064 | 0.67 | KCNH2 (0.44) | ELANEKCNH2TDP1DNM1NPC1 | |
| SCHEMBL45208 | 0.67 | KCNH2 (0.48) | LMNAKCNH2HCAR3CYP3A4TDP1 | |
| SCHEMBL13271928 | 0.67 | ELANE (0.37) | LMNAELANEHCAR3SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046271-B1 | PHOTOSENSITIVE COMPOSITIONS AND ELEMENTS CONTAINING SUBSTITUTED HYDROXYLAMINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |
| US-4332884-A | USING A DIOXIME CHELATING AGENT | RICOH CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| EP-0046271-A1 | Photosensitive compositions and elements containing substituted hydroxylamine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |
| US-4298678-A | PHOTOOXIDANT AND LEUCO DYE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-03 | — | — | US | disclosed |