Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15376731 | 0.82 | LMNA (0.48) | LMNAKMT2ATDP1MEN1THRB | |
| Hydrochloric Acid SCHEMBL27801537 | 0.80 | LMNA (0.47) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL5843818 | 0.80 | LMNA (0.44) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL26136641 | 0.79 | SRC (0.62) | LMNASRCCYP2D6ALDH1A1TSHR | |
| SCHEMBL7262264 | 0.76 | LMNA (0.40) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL10715232 | 0.76 | FABP4 (0.42) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL4896893 | 0.76 | LMNA (0.55) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL8953578 | 0.74 | KMT2A (0.39) | LMNAKMT2ATDP1MEN1THRB | |
| Ortho-Phthalaldehyde SCHEMBL5968146 | 0.74 | LMNA (0.77) | LMNAKMT2ATDP1MEN1THRB | |
| SCHEMBL1274051 | 0.74 | CES2 (0.50) | LMNAKMT2AMEN1SRCCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316995-A | FROM P-HYDROXYBENZALDEHYDE MALONIC ACID | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-02-23 | — | — | US | claimed |
| CN-109311924-A | Improved preparation of vaccines against streptococcus pneumoniae type 3 | 马克斯·普朗克科学促进学会 | 2019-02-05 | — | — | CN | disclosed |