SCHEMBL5843818

SCHEMBL5843818

CC(C(=O)O)c1ccccc1C=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PTGS2 P35354 7/20 0.44
CXCL8 P10145 2/20 0.44
MMP2 P08253 2/20 0.44
MMP9 P14780 2/20 0.44
MMP8 P22894 2/20 0.44
MMP12 P39900 2/20 0.44
MMP13 P45452 2/20 0.44
MMP14 P50281 2/20 0.44
MMP16 P51512 2/20 0.44
MMP1 P03956 1/20 0.44
PTGS1 P23219 5/20 0.43
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
TRIM24 O15164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5742366 0.83 CXCL8 (0.45) LMNAMEN1THRBBLMKMT2A
SCHEMBL2928008 0.83 PTGS2 (0.43) LMNAPTGS2CXCL8MMP2MMP9
SCHEMBL2204495 0.81 PTGS2 (0.56) LMNAMEN1KMT2APTGS2CXCL8
SCHEMBL8099514 0.80 CA1 (0.53) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL10591005 0.80 TRPA1 (0.47) LMNATDP1PTGS2CXCL8MMP2
SCHEMBL8099512 0.80 CA1 (0.53) PTGS2CXCL8MMP2MMP9MMP8
SCHEMBL11228899 0.80 LMNA (0.48) LMNAMEN1THRBBLMKMT2A
SCHEMBL29243911 0.80 CXCL8 (0.44) LMNAMEN1THRBBLMKMT2A
SCHEMBL9715735 0.79 ALDH1A1 (0.44) LMNAMEN1BLMKMT2APTGS2
SCHEMBL15376731 0.78 LMNA (0.48) LMNAMEN1THRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984716-B2 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2006-01-10 US claimed
US-20040077825-A1 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US claimed
CN-115754042-B Method for detecting impurity alpha-formylphenyl methyl acetate in ipratropium bromide 石家庄四药有限公司 2023-06-09 CN disclosed
US-20040077821-A1 Flame retarding resin composition CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed