Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 12/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123335 | 0.94 | LPAR1 (0.52) | LPAR1LPAR5LTA4HFFAR1 | |
| SCHEMBL1122959 | 0.92 | LPAR1 (0.54) | LPAR1LPAR5LTA4HHDAC1HDAC6 | |
| SCHEMBL1122692 | 0.87 | LPAR1 (0.55) | LPAR1LPAR5LTA4HHDAC1HDAC6 | |
| SCHEMBL1122949 | 0.86 | FFAR1 (0.52) | FFAR1 | |
| SCHEMBL1122912 | 0.86 | LPAR1 (0.49) | LPAR1LPAR5FFAR1 | |
| SCHEMBL1123394 | 0.86 | KMT2A (0.52) | FFAR1 | |
| SCHEMBL1122837 | 0.84 | PPARG (0.51) | LPAR1LPAR5FFAR1 | |
| SCHEMBL1123395 | 0.83 | F10 (0.51) | LPAR1HDAC1HDAC6 | |
| SCHEMBL1123247 | 0.82 | SLC2A1 (0.47) | LPAR1HDAC1HDAC6 | |
| SCHEMBL1123189 | 0.82 | LPAR1 (0.51) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |