Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.52 |
| ▸ | PTGES | O14684 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122952 | 0.94 | LPAR1 (0.53) | LPAR1LPAR5FFAR1LTA4H | |
| SCHEMBL1122692 | 0.93 | LPAR1 (0.55) | LPAR1LPAR5PTGESSLC2A1LTA4H | |
| SCHEMBL1122912 | 0.93 | LPAR1 (0.49) | LPAR1LPAR5PTGESSLC2A1FFAR1 | |
| SCHEMBL1122949 | 0.91 | FFAR1 (0.52) | PTGESSLC2A1FFAR1PPARGPPARA | |
| SCHEMBL1122837 | 0.91 | PPARG (0.51) | LPAR1LPAR5PTGESSLC2A1FFAR1 | |
| SCHEMBL1122959 | 0.88 | LPAR1 (0.54) | LPAR1LPAR5SLC2A1LTA4H | |
| SCHEMBL1123244 | 0.86 | LPAR1 (0.52) | LPAR1LPAR5PTGESSLC2A1PPARG | |
| SCHEMBL1123557 | 0.85 | PTGES (0.52) | PTGESSLC2A1FFAR1PPARGALOX5 | |
| SCHEMBL1123394 | 0.84 | KMT2A (0.52) | PTGESFFAR1FFAR4PPARGPPARA | |
| SCHEMBL1123277 | 0.84 | PPARG (0.49) | LPAR1LPAR5PTGESSLC2A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |