Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123270 | 0.92 | ALOX5 (0.53) | L3MBTL1ALOX5LPAR1LPAR5PTGES | |
| SCHEMBL1122799 | 0.87 | L3MBTL1 (0.53) | L3MBTL1ALOX5LPAR1LPAR5PTGS1 | |
| SCHEMBL1122914 | 0.86 | KMT2A (0.51) | ALOX5PTGESPPARGPPARANR4A2 | |
| SCHEMBL1122837 | 0.85 | PPARG (0.51) | L3MBTL1ALOX5LPAR1LPAR5PTGES | |
| SCHEMBL1123016 | 0.84 | RAB9A (0.51) | ALOX5LPAR1LPAR5PTGESLMNA | |
| SCHEMBL1122949 | 0.83 | FFAR1 (0.52) | ALOX5PTGESPPARGPPARABCHE | |
| SCHEMBL1123189 | 0.83 | LPAR1 (0.51) | L3MBTL1LPAR1LPAR5PPARGPPARA | |
| SCHEMBL1123394 | 0.82 | KMT2A (0.52) | L3MBTL1PTGESPPARGPPARANR4A2 | |
| SCHEMBL1123268 | 0.82 | BCHE (0.56) | L3MBTL1ALOX5LPAR1LPAR5PTGS1 | |
| SCHEMBL11840883 | 0.81 | L3MBTL1 (0.57) | L3MBTL1ALOX5PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |