Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30041622 | 0.78 | HTR6 (0.48) | HTR6CES1MAOATSHRNOS3 | |
| SCHEMBL6925588 | 0.78 | HTR6 (0.48) | HTR6CES1MAOATSHRNOS3 | |
| SCHEMBL9321655 | 0.75 | MAOA (0.50) | HTR6CES1MAOANPC1RAB9A | |
| SCHEMBL6624132 | 0.71 | HTR6 (0.43) | HTR6TSHRNOS3NPC1RAB9A | |
| SCHEMBL276262 | 0.65 | MAOA (0.41) | HTR6CES1MAOANPC1RAB9A | |
| SCHEMBL26013515 | 0.63 | ALDH1A1 (0.48) | HTR6TSHRNOS3NPC1RAB9A | |
| SCHEMBL7960264 | 0.62 | HTR6 (0.41) | HTR6CES1MAOATSHRALDH1A1 | |
| SCHEMBL4448887 | 0.62 | HTR6 (0.41) | HTR6CES1MAOATSHRNOS3 | |
| SCHEMBL10532536 | 0.62 | ALDH1A1 (0.46) | HTR6CES1TSHRKDM4EALDH1A1 | |
| SCHEMBL6035252 | 0.62 | MAOA (0.34) | CES1MAOAMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323497-A | Water-soluble disazo dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-06 | — | — | US | disclosed |