Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 13/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.55 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | BAX | Q07812 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123228 | 0.93 | GPR132 (0.60) | GPR132PTPN1CMKLR2CMKLR1ITGB3 | |
| SCHEMBL1123437 | 0.89 | PTPN1 (0.67) | GPR132PTPN1ITGB3ITGA2BPPARG | |
| SCHEMBL1123368 | 0.88 | GPR132 (0.60) | GPR132PTPN1CMKLR2CMKLR1ITGB3 | |
| SCHEMBL1123431 | 0.88 | GPR132 (0.61) | GPR132PTPN1CMKLR2CMKLR1ITGB3 | |
| SCHEMBL1122981 | 0.84 | ITGB2 (0.52) | GPR132PPARG | |
| SCHEMBL1123378 | 0.84 | GPR132 (0.57) | GPR132PTPN1CMKLR2CMKLR1ITGB3 | |
| SCHEMBL1123050 | 0.81 | PTPN1 (0.69) | GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL1122721 | 0.81 | PTPN1 (0.68) | GPR132PTPN1ITGB3ITGA2BPPARG | |
| SCHEMBL1123282 | 0.80 | PTPN1 (0.58) | GPR132PTPN1CMKLR2CMKLR1ITGB3 | |
| SCHEMBL1123517 | 0.78 | PTPN1 (0.64) | GPR132PTPN1ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |