Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 14/20 | 0.61 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.54 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123282 | 0.92 | PTPN1 (0.58) | GPR132CMKLR2CMKLR1PTPN1MME | |
| SCHEMBL1123228 | 0.90 | GPR132 (0.60) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123192 | 0.88 | GPR132 (0.63) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123368 | 0.85 | GPR132 (0.60) | GPR132CMKLR2CMKLR1PTPN1ITGB1 | |
| SCHEMBL1123378 | 0.85 | GPR132 (0.57) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL10816310 | 0.83 | GPR132 (0.66) | GPR132CMKLR2CMKLR1PTPN1MME | |
| SCHEMBL1122807 | 0.79 | GPR132 (0.82) | GPR132CMKLR2CMKLR1PTPN1 | |
| SCHEMBL1123050 | 0.78 | PTPN1 (0.69) | GPR132PTPN1ITGB1ITGA5ITGB3 | |
| SCHEMBL1122981 | 0.78 | ITGB2 (0.52) | GPR132 | |
| SCHEMBL1122844 | 0.78 | MEN1 (0.63) | GPR132CMKLR2CMKLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |