Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 14/20 | 0.60 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.53 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123192 | 0.93 | GPR132 (0.63) | GPR132CMKLR2CMKLR1PTPN1PPARG | |
| SCHEMBL1123431 | 0.90 | GPR132 (0.61) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123368 | 0.84 | GPR132 (0.60) | GPR132CMKLR2CMKLR1PTPN1CTSL | |
| SCHEMBL1122981 | 0.84 | ITGB2 (0.52) | GPR132PPARG | |
| SCHEMBL1123378 | 0.84 | GPR132 (0.57) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123282 | 0.82 | PTPN1 (0.58) | GPR132CMKLR2CMKLR1PTPN1ITGB3 | |
| SCHEMBL1123437 | 0.82 | PTPN1 (0.67) | GPR132PTPN1PPARGITGB3ITGA2B | |
| SCHEMBL1123050 | 0.77 | PTPN1 (0.69) | GPR132PTPN1CTSBCTSSCTSK | |
| SCHEMBL1122844 | 0.77 | MEN1 (0.63) | GPR132CMKLR2CMKLR1PPARG | |
| SCHEMBL1122721 | 0.77 | PTPN1 (0.68) | GPR132PTPN1PPARGITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |