Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122636 | 0.88 | BCHE (0.50) | NPC1LMNARAB9AKMT2ABCHE | |
| SCHEMBL1123250 | 0.87 | L3MBTL1 (0.53) | L3MBTL1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL1123230 | 0.87 | LPAR1 (0.48) | NPC1LMNALTA4HALOX5LPAR1 | |
| SCHEMBL1123181 | 0.85 | LPAR1 (0.49) | MAPTLTA4HKMT2ALPAR1LPAR5 | |
| SCHEMBL1123229 | 0.82 | SLC2A1 (0.55) | NPC1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL1122802 | 0.82 | L3MBTL1 (0.47) | L3MBTL1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL1123467 | 0.82 | NPC1 (0.55) | L3MBTL1NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL1123052 | 0.81 | NR4A1 (0.45) | NPC1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL1123324 | 0.80 | LPAR1 (0.46) | L3MBTL1ALDH1A1MEN1KMT2ALPAR1 | |
| SCHEMBL1123270 | 0.80 | ALOX5 (0.53) | L3MBTL1NPC1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |