Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.62 |
| ▸ | MMP9 | P14780 | 4/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.62 |
| ▸ | MMP8 | P22894 | 2/20 | 0.62 |
| ▸ | MMP3 | P08254 | 1/20 | 0.62 |
| ▸ | MMP7 | P09237 | 1/20 | 0.62 |
| ▸ | MMP14 | P50281 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711952 | 0.91 | ALDH1A1 (0.73) | MMP2MMP9MMP1MMP8KMT2A | |
| SCHEMBL10536063 | 0.83 | PKM (0.70) | MMP2MMP9MMP1MMP8MMP3 | |
| SCHEMBL9815431 | 0.83 | PKM (0.70) | MMP2MMP9MMP1MMP8MMP3 | |
| SCHEMBL9518669 | 0.82 | ALDH1A1 (0.57) | MMP2MMP9MMP1MMP8KMT2A | |
| SCHEMBL11239362 | 0.81 | MMP2 (0.60) | MMP2MMP9MMP1MMP8MMP3 | |
| SCHEMBL6516221 | 0.80 | KMT2A (0.73) | KMT2AALDH1A1POLBMAPTMEN1 | |
| SCHEMBL31500692 | 0.80 | MMP2 (0.59) | MMP2MMP9MMP1MMP8MMP3 | |
| SCHEMBL12717525 | 0.80 | MMP2 (0.74) | MMP2MMP9MMP1MMP8MMP3 | |
| SCHEMBL11238167 | 0.79 | CA2 (0.56) | KMT2AALDH1A1POLBMAPTKDM4E | |
| SCHEMBL9472886 | 0.79 | CA2 (0.65) | KMT2AALDH1A1POLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346046-A | FROM AMINOARYL-B-HYDROXYETHYLSULFONE AND SULFURIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-24 | — | — | US | disclosed |