Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711952 | 0.88 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL948303 | 0.86 | KDM4E (0.78) | ALDH1A1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL11233004 | 0.82 | MMP2 (0.62) | ALDH1A1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL9746587 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL9495391 | 0.81 | TP53 (0.49) | ALDH1A1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL9645228 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL950400 | 0.80 | SNCA (0.59) | KMT2AMAPTPOLBKDM4EMEN1 | |
| SCHEMBL8577441 | 0.79 | MEN1 (0.68) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| Water SCHEMBL11035834 | 0.78 | SNCA (0.58) | KMT2AMAPTPOLBKDM4EMEN1 | |
| SCHEMBL949134 | 0.78 | CA2 (0.53) | ALDH1A1KMT2AMAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343262-B1 | FIBRE-REACTIVE AZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR DYEING HYDROXY- AND/OR CARBOXAMIDE GROUPS CONTAINING FIBRE-MATERIAL | HOECHST CELANESE CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| EP-0343262-A1 | Fibre-reactive azo dyes, process for their preparation and their use for dyeing hydroxy- and/or carboxamide groups containing fibre-material | HOECHST CELANESE CORPORATION (US) | 1989-11-29 | — | — | EP | disclosed |