Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238700 | 0.87 | POLB (0.39) | KDM4EHSD17B10GAAHPGDALDH1A1 | |
| SCHEMBL11235309 | 0.83 | ALDH1A1 (0.58) | KDM4EGAAALDH1A1POLBLMNA | |
| SCHEMBL11231843 | 0.78 | PDE3B (0.51) | KDM4EGAAHPGDLMNARXFP1 | |
| SCHEMBL11243686 | 0.78 | KDM4E (0.36) | KDM4EHSD17B10HPGDALDH1A1MAPK1 | |
| SCHEMBL11248993 | 0.76 | GAA (0.50) | KDM4EHSD17B10GAAHPGDPKM | |
| SCHEMBL10851783 | 0.76 | KDM4E (0.60) | KDM4EHSD17B10GAAHPGDPKM | |
| SCHEMBL11451200 | 0.74 | DYRK1A (0.44) | KDM4EHSD17B10GAAHPGDLCK | |
| SCHEMBL11232009 | 0.74 | KDM4E (0.61) | KDM4EHSD17B10GAAHPGDALDH1A1 | |
| SCHEMBL11239062 | 0.73 | KDM4E (0.50) | KDM4EHSD17B10GAAHPGDALDH1A1 | |
| SCHEMBL10989508 | 0.72 | GAA (0.49) | KDM4EHSD17B10GAAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312875-A | 5-(Pyridinyl)-6-(lower-alkyl)-2(1H)-pyridinones, 1,2-dihydro-2-oxo-5-(pyridinyl)-6-(lower-alkyl)nicotinic acids and lower-alkyl esters thereof, and cardiotonic use thereof | STERLING DRUG INC. (US) | 1982-01-26 | — | — | US | disclosed |