Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.46 |
| ▸ | PDE4A | P27815 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820403 | 0.78 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DSQOR | |
| SCHEMBL28136118 | 0.75 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DMAPT | |
| SCHEMBL21331773 | 0.75 | BACE1 (0.42) | PDE4BPDE4APDE4CPDE4DSQOR | |
| SCHEMBL12325398 | 0.74 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DSQOR | |
| SCHEMBL1069430 | 0.74 | ALDH1A1 (0.43) | PDE4BPDE4APDE4CPDE4DKMT2A | |
| SCHEMBL20553969 | 0.74 | SQOR (0.42) | PDE4BPDE4APDE4CPDE4DSQOR | |
| SCHEMBL7823588 | 0.73 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DSQOR | |
| SCHEMBL2096573 | 0.72 | PDE4B (0.55) | PDE4BPDE4APDE4CPDE4DSQOR | |
| SCHEMBL360305 | 0.71 | SQOR (0.44) | PDE4BPDE4APDE4CPDE4DSQOR | |
| SCHEMBL7823294 | 0.71 | PGR (0.42) | PDE4BPDE4APDE4CPDE4DSQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546089-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TransTech Pharma Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004014844-A2 | ARYL AND HETEROARYL COMPOUNDS AND METHODS TO MODULATE COAGULATION | TRANSTECH PHARMA, INC. (US) | 2004-02-19 | — | — | WO | claimed |