SCHEMBL6567310

SCHEMBL6567310

Cc1ccc(O)c(-c2cc(C)cc(-c3cc(C)ccc3O)c2O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.54
TDP1 Q9NUW8 3/20 0.52
TP53 P04637 2/20 0.52
AMY1A P0DUB6 1/20 0.50
IDO1 P14902 1/20 0.48
ALOX15 P16050 5/20 0.48
HSD17B10 Q99714 4/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 6/20 0.46
MAPT P10636 5/20 0.46
MEN1 O00255 3/20 0.46
LMNA P02545 3/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 2/20 0.46
ALOX12 P18054 2/20 0.46
SELL P14151 1/20 0.46
SELP P16109 1/20 0.46
SELE P16581 1/20 0.46
KDM4E B2RXH2 2/20 0.44
USP2 O75604 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18826296 0.91 TRPA1 (0.56) TRPA1TDP1TP53AMY1AIDO1
SCHEMBL30046067 0.90 TRPA1 (0.65) TRPA1TDP1TP53AMY1AIDO1
SCHEMBL278520 0.90 TRPA1 (0.65) TRPA1TDP1TP53AMY1AIDO1
SCHEMBL29763149 0.90 TRPA1 (0.65) TRPA1TDP1TP53AMY1AIDO1
SCHEMBL16014627 0.82 ACHE (0.48) TRPA1TDP1TP53AMY1AIDO1
SCHEMBL11233686 0.82 ALDH1A1 (0.59) TRPA1TDP1TP53AMY1AIDO1
SCHEMBL17431237 0.81 TRPA1 (0.41) TRPA1TDP1TP53AMY1AIDO1
SCHEMBL18171927 0.81 TDP1 (0.58) TRPA1TDP1TP53IDO1ALOX15
SCHEMBL17753391 0.81 TRPA1 (0.54) TRPA1TDP1TP53AMY1AIDO1
Sulfur Dioxide SCHEMBL20526199 0.81 TRPA1 (0.54) TRPA1TDP1TP53AMY1AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040225048-A1 Vibration damping material composition TITECS JAPAN CORPORATION (JP) 2004-11-11 US claimed
EP-1408075-A1 Vibration damping material composition Titecs Japan Corporation (JP) 2004-04-14 EP claimed
US-20040225048-A1 Vibration damping material composition TITECS JAPAN CORPORATION (JP) 2004-11-11 US disclosed
EP-1408075-A1 Vibration damping material composition Titecs Japan Corporation (JP) 2004-04-14 EP disclosed
US-4476007-A PERMSELECTIVE MEMBRANES; QUANTITATIVE ANALYSIS FOR BIOLOGICAL CELLS AND SERUMS EASTMAN KODAK COMPANY (US) 1984-10-09 US disclosed
US-3931108-A DIHYDROXY AROMATIC WITH PHOSGENE BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed