Nitrophenolate

Nitrophenolate

SCHEMBL11233778

Nc1ccccc1N.O=[N+]([O-])c1ccccc1O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 4/20 0.55
MAPK1 P28482 3/20 0.53
ALOX15 P16050 2/20 0.53
HSD17B10 Q99714 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
PDE7A Q13946 1/20 0.53
CTSB P07858 1/20 0.48
TSHR P16473 2/20 0.48
KCNMA1 Q12791 1/20 0.46
ALDH1A1 P00352 2/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
CYP3A4 P08684 1/20 0.46
PLAU P00749 1/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
CTSD P07339 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrophenolate SCHEMBL28125078 0.94 ALOX15 (0.58) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL5387922 0.90 GPR35 (0.61) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL22033631 0.90 GPR35 (0.61) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL28029048 0.89 GPR35 (0.65) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL26026 0.89 GPR35 (0.65) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL29360402 0.89 GPR35 (0.65) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL10996867 0.87 GPR35 (0.63) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL16553333 0.87 GPR35 (0.63) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL10496084 0.87 GPR35 (0.63) GPR35MAPK1ALOX15HSD17B10L3MBTL1
Nitrophenolate SCHEMBL325409 0.87 GPR35 (0.63) GPR35MAPK1ALOX15HSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4330291-A Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1982-05-18 US disclosed