Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 9/20 | 0.68 |
| ▸ | GRN | P28799 | 1/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.48 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123392 | 0.93 | GPR132 (0.78) | GPR132GRNSORT1CTSSCTSL | |
| SCHEMBL1123119 | 0.92 | GPR132 (0.77) | GPR132GRNSORT1CTSSPTPN1 | |
| SCHEMBL1123574 | 0.92 | GPR132 (0.58) | GPR132CTSSPTPN1CTSLCTSB | |
| SCHEMBL1123575 | 0.92 | GPR132 (0.58) | GPR132CTSSPTPN1CTSLCTSB | |
| SCHEMBL1122784 | 0.89 | GPR132 (0.62) | GPR132GRNSORT1CTSSCTSL | |
| SCHEMBL1122740 | 0.85 | GPR132 (0.66) | GPR132CTSSCTSLCTSBCMKLR2 | |
| SCHEMBL1123253 | 0.84 | GPR132 (0.65) | GPR132CTSSPTPN1CTSLCTSB | |
| SCHEMBL1123135 | 0.83 | GPR132 (0.54) | GPR132GRNSORT1CTSSPTPN1 | |
| SCHEMBL1122875 | 0.82 | GPR132 (0.79) | GPR132PTPN1CMKLR2CMKLR1PPARG | |
| SCHEMBL27658925 | 0.82 | GPR132 (0.79) | GPR132PTPN1CMKLR2CMKLR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |