Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.62 |
| ▸ | GRN | P28799 | 2/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123151 | 0.91 | MAOB (0.52) | GPR132MAOBPARP15PARP14PARP10 | |
| SCHEMBL1123390 | 0.89 | GPR132 (0.68) | GPR132GRNSORT1CTSSCTSL | |
| SCHEMBL1123119 | 0.83 | GPR132 (0.77) | GPR132GRNSORT1CTSSCTSL | |
| SCHEMBL1123392 | 0.82 | GPR132 (0.78) | GPR132GRNSORT1CTSSCTSL | |
| SCHEMBL1123575 | 0.81 | GPR132 (0.58) | GPR132CTSSCTSLCTSBCTSK | |
| SCHEMBL1123574 | 0.81 | GPR132 (0.58) | GPR132CTSSCTSLCTSBCTSK | |
| SCHEMBL27658953 | 0.81 | GPR132 (0.67) | GPR132MAOBPARP15PARP14PARP10 | |
| SCHEMBL1123679 | 0.81 | GPR132 (0.67) | GPR132MAOBPARP15PARP14PARP10 | |
| SCHEMBL1123135 | 0.80 | GPR132 (0.54) | GPR132GRNSORT1CTSSCTSL | |
| SCHEMBL1122814 | 0.79 | GPR132 (0.53) | GPR132GRNSORT1CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |