Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 7/20 | 0.66 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.48 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123253 | 0.95 | GPR132 (0.65) | GPR132CTSLCTSSSMPD1CTSK | |
| SCHEMBL1123575 | 0.94 | GPR132 (0.58) | GPR132CTSLCTSSCTSKCTSB | |
| SCHEMBL1123574 | 0.94 | GPR132 (0.58) | GPR132CTSLCTSSCTSKCTSB | |
| SCHEMBL1123392 | 0.91 | GPR132 (0.78) | GPR132CTSLCTSSSMPD1CTSK | |
| SCHEMBL1123156 | 0.87 | GPR132 (0.58) | GPR132CTSLCTSSSMPD1CTSK | |
| SCHEMBL1123119 | 0.87 | GPR132 (0.77) | GPR132CTSLCTSSSMPD1CMKLR2 | |
| SCHEMBL1123390 | 0.85 | GPR132 (0.68) | GPR132CTSLCTSSCTSKCTSB | |
| SCHEMBL1123158 | 0.84 | GPR132 (0.77) | GPR132SMPD1NR4A2CMKLR2CMKLR1 | |
| SCHEMBL1123151 | 0.82 | MAOB (0.52) | GPR132CTSLCTSSCTSKCTSB | |
| SCHEMBL4893620 | 0.82 | GPR132 (0.69) | GPR132SMPD1CTSKNR4A2CMKLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |