SCHEMBL1123463

SCHEMBL1123463

C=Cc1cccc(N)c1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.56
TSHR P16473 3/20 0.56
PIK3CA P42336 1/20 0.56
ALDH1A1 P00352 5/20 0.46
CD44 P16070 1/20 0.39
TDP1 Q9NUW8 3/20 0.36
TP53 P04637 2/20 0.35
HPGD P15428 3/20 0.35
HSD17B10 Q99714 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
ESR2 Q92731 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TDP2 O95551 1/20 0.31
NSD2 O96028 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6427634 0.83 ALDH1A1 (0.46) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL18177295 0.82 ALDH1A1 (0.48) CYP3A4TSHRPIK3CAALDH1A1CD44
SCHEMBL13210354 0.79 CYP3A4 (0.48) CYP3A4TSHRPIK3CAALDH1A1CD44
SCHEMBL3831451 0.79 CYP3A4 (0.40) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL1845335 0.77 TSHR (0.56) CYP3A4TSHRPIK3CAALDH1A1CD44
SCHEMBL18434540 0.77 CYP3A4 (0.45) CYP3A4TSHRPIK3CAALDH1A1CD44
SCHEMBL242300 0.76 CD44 (0.42) CYP3A4TSHRPIK3CAALDH1A1CD44
SCHEMBL29392787 0.76 TRPA1 (0.42) TSHRALDH1A1CD44TDP1TP53
SCHEMBL20540071 0.76 ALDH1A1 (0.41) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL28496 0.76 TRPA1 (0.42) TSHRALDH1A1CD44TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9147603-B2 Polymer grafting for enhanced dielectric and interconnect material adhesion INTEL CORPORATION (US) 2015-09-29 US claimed
US-20150206793-A1 POLYMER GRAFTING FOR ENHANCED DIELECTRIC AND INTERCONNECT MATERIAL ADHESION INTEL CORPORATION 2015-07-23 US claimed
EP-1397429-B1 COMPOSITE PARTICLES, DERIVED CONJUGATES, PREPARATION METHOD THEREOF AND APPLICATIONS OF SAME BIO MERIEUX (FR) 2015-04-01 EP claimed
CN-102117886-B Modified electrodes using functional organic materials and electronic devices therefrom GEN ELECTRIC 2013-03-06 CN claimed
CN-102117886-A Modified electrodes using functional organic materials and electronic devices therefrom GEN ELECTRIC 2011-07-06 CN claimed
JP-4272513-B2 2009-06-03 JP claimed
CN-101160673-A Modified electrodes using functional organic materials and electronic devices therefrom GEN ELECTRIC (US) 2008-04-09 CN claimed
JP-2004533530-A 2004-11-04 JP claimed
EP-1397429-A1 COMPOSITE PARTICLES, DERIVED CONJUGATES, PREPARATION METHOD THEREOF AND APPLICATIONS OF SAME BIO MERIEUX (FR) 2004-03-17 EP claimed
WO-2003004559-A1 COMPOSITE PARTICLES, DERIVED CONJUGATES, PREPARATION METHOD THEREOF AND APPLICATIONS OF SAME BIO MERIEUX (FR) 2003-01-16 WO claimed
WO-2001033224-A1 COMPOSITE PARTICLES, DERIVED CONJUGATES AND THEIR CONJUGATES WITH BIOMOLECULES BIO MERIEUX (FR) 2001-05-10 WO claimed
US-20260043166-A1 DUAL ACTIVITY OF COPPER MODIFIED NANOTEXTURED STAINLESS STEEL GEORGIA TECH RES INST (US) 2026-02-12 US disclosed
US-20230416658-A1 COMPOSITIONS COMPRISING PROTONATED TRIAZACYCLIC COMPOUNDS AND MANGANESE(II) ACETATE, MANUFACTURING THEREOF, AND BLEACHING AND CLEANING AGENT COMPRISING SAME CATEXEL GMBH (DE) 2023-12-28 US disclosed
EP-4296344-A1 COMPOSITIONS COMPRISING PROTONATED TRIAZACYCLIC COMPOUNDS AND MANGANESE(II) ACETATE, MANUFACTURING THEREOF, AND BLEACHING AND CLEANING AGENT COMPRISING SAME WeylChem Performance Products GmbH (DE) 2023-12-27 EP disclosed
US-11746252-B2 Composition, coating, coating film, back sheet for solar cell module and solar cell module DAIKIN FLUOROCHEMICALS (CHINA) CO., LTD. (CN) 2023-09-05 US disclosed
WO-1997046570-A1 OLIGORIBONUCLEOTIDES AND RIBONUCLEASES FOR CLEAVING RNA ISIS PHARMACEUTICALS, INC. (US) 1997-12-11 WO disclosed
US-5391667-A Blend with ethynically unsaturated monomer having atleast one amine or amine-displaceable functionality and crosslinking agent; supports ISIS PHARMACEUTICALS (US) 1995-02-21 US disclosed
US-5326489-A Sulfonated polymer NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
EP-0523300-B1 Electrorheological fluids NIPPON CATALYTIC CHEM IND (JP) 1994-01-19 EP disclosed
EP-0523300-A1 Electrorheological fluids NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) 1993-01-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260043166-A1 DUAL ACTIVITY OF COPPER MODIFIED NANOTEXTURED STAINLESS STEEL CLPP, SOD1, CUTA CYP3A4 2049/4885TSHR 775/4885PIK3CA 1729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.