Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452431 | 0.87 | KMT2A (0.61) | KMT2ACYP2C19KDM4EMEN1CYP1A2 | |
| SCHEMBL11247737 | 0.87 | KMT2A (0.64) | KMT2ACYP2C19KDM4EMEN1CYP1A2 | |
| SCHEMBL11250348 | 0.81 | L3MBTL1 (0.50) | KMT2AMEN1L3MBTL1MAPK8MAPT | |
| SCHEMBL10970151 | 0.78 | KMT2A (0.57) | KMT2ACYP2C19KDM4EMEN1CYP1A2 | |
| SCHEMBL10973036 | 0.76 | KMT2A (0.57) | KMT2ACYP2C19KDM4EMEN1CYP1A2 | |
| SCHEMBL11238903 | 0.75 | MET (0.45) | KMT2ACYP2C19MAPK8MAPTPDE4A | |
| SCHEMBL10971447 | 0.74 | KMT2A (0.78) | KMT2ACYP2C19KDM4EMEN1CYP1A2 | |
| SCHEMBL11243535 | 0.74 | GPBAR1 (0.44) | KMT2ACYP2C19KDM4EL3MBTL1MAPK8 | |
| SCHEMBL8780573 | 0.73 | P2RY1 (0.48) | KMT2ACYP2C19KDM4EMEN1CYP1A2 | |
| SCHEMBL27809949 | 0.70 | RAB9A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053011-A1 | New herbicidal nicotinamide derivatives | MAY & BAKER LIMITED (GB) | 1982-06-02 | — | — | EP | disclosed |