Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238903 | 0.93 | MET (0.45) | GPBAR1POLBKMT2ACYP2C9CYP2C19 | |
| SCHEMBL3137908 | 0.76 | GPBAR1 (0.72) | GPBAR1POLBKMT2AKDM4ECYP2C9 | |
| SCHEMBL16487052 | 0.76 | KMT2A (0.53) | GPBAR1POLBKMT2AKDM4ETDP1 | |
| SCHEMBL4302001 | 0.75 | KMT2A (0.49) | GPBAR1POLBKMT2AKDM4ETDP1 | |
| SCHEMBL11247737 | 0.74 | KMT2A (0.64) | KMT2AKDM4ECYP2C19ALDH1A1LMNA | |
| SCHEMBL11234692 | 0.74 | KMT2A (0.47) | POLBKMT2AKDM4ECYP2C9CYP2C19 | |
| SCHEMBL10977484 | 0.73 | P2RY1 (0.55) | GPBAR1KMT2AKDM4ECYP2C9CYP2C19 | |
| SCHEMBL6452431 | 0.72 | KMT2A (0.61) | KMT2AKDM4ECYP2C19METL3MBTL1 | |
| SCHEMBL11250348 | 0.71 | L3MBTL1 (0.50) | POLBKMT2ALMNAL3MBTL1MAPK8 | |
| SCHEMBL27809949 | 0.70 | RAB9A (0.52) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053011-A1 | New herbicidal nicotinamide derivatives | MAY & BAKER LIMITED (GB) | 1982-06-02 | — | — | EP | claimed |