Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766523 | 0.86 | XDH (0.31) | — | |
| SCHEMBL472874 | 0.76 | LMNA (0.34) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 | |
| SCHEMBL11563083 | 0.75 | NOS3 (0.39) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL822111 | 0.75 | HRH4 (0.40) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL5833897 | 0.75 | NOS3 (0.44) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL14300643 | 0.75 | NOS3 (0.39) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL11565601 | 0.75 | NOS3 (0.39) | NOS3NOS1NOS2TRPA1SIGMAR1 | |
| SCHEMBL9380549 | 0.74 | MAPT (0.47) | NOS3NOS1NOS2HRH4NPC1 | |
| SCHEMBL9006274 | 0.73 | HRH4 (0.32) | NOS3NOS1NOS2HRH4ADRA1D | |
| SCHEMBL20581797 | 0.72 | TRPA1 (0.40) | NOS3NOS1NOS2TRPA1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4139274-A | Apparatus for changing color | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-02-13 | — | — | US | disclosed |