Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766523 | 0.81 | XDH (0.31) | GABRA1GABRB2 | |
| SCHEMBL3014252 | 0.78 | ALDH1A1 (0.36) | LMNAL3MBTL1HTTALDH1A1CASP3 | |
| SCHEMBL14311341 | 0.78 | ALDH1A1 (0.34) | LMNAL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL4764684 | 0.78 | SHMT2 (0.39) | LMNAL3MBTL1HTTALDH1A1CASP3 | |
| SCHEMBL19211201 | 0.78 | ALDH1A1 (0.34) | LMNAL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL2363208 | 0.77 | CHEK1 (0.36) | GAACES1MEN1KMT2A | |
| SCHEMBL11234716 | 0.76 | NOS3 (0.36) | LMNAALDH1A1MAPTPKMBCHE | |
| SCHEMBL9175519 | 0.75 | SHMT2 (0.34) | LMNAL3MBTL1HTTALDH1A1KDM4E | |
| SCHEMBL9176975 | 0.74 | KDM4E (0.32) | LMNAL3MBTL1HTTALDH1A1KDM4E | |
| SCHEMBL8780480 | 0.73 | PTPN1 (0.35) | ALDH1A1KDM4EMAPTCES1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117224534-A | Lactam for treating skin lesions | 联合利华知识产权控股有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023227856-A1 | AN ELECTROCHEMICAL SENSOR AND METHOD FOR DETECTING PATHOGENIC METABOLITES | UNIVERSITY OF DURHAM (GB) | 2023-11-30 | — | — | WO | disclosed |
| US-11596626-B2 | Compound for use against pathogenic Neisseria and Haemophilus species and Moraxella catarrhalis | Universität Konstanz (DE) | 2023-03-07 | — | — | US | disclosed |
| US-20210393586-A1 | Compounds for Use in the Treatment of Bacterial Infections | Universität Konstanz (DE) | 2021-12-23 | — | — | US | disclosed |
| US-11160787-B2 | 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one for use in the treatment of gram negative bacterial infections | CONOPCO, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-11083706-B2 | Lactams for use in the treatment of skin lesions | CONOPCO, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| EP-3833338-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | Universität Konstanz (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-20210169869-A1 | Compound for Use Against Pathogenic Neisseria and Haemophilus Species and Moraxella Catarrhalis | Universität Wien (AT) | 2021-06-10 | — | — | US | disclosed |
| US-10875830-B2 | Method of treatment | Conopeo, Inc. (US) | 2020-12-29 | — | — | US | disclosed |
| US-10863748-B2 | Antibacterial products and processes for preparing antibacterial products from maple syrup | LUONG JOHN HA THANH (CA) | 2020-12-15 | — | — | US | disclosed |
| EP-2598651-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | Sanofi-Aventis Deutschland GmbH (DE) | 2013-06-05 | — | — | EP | disclosed |
| US-20130123360-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012154651-A2 | MOLECULAR ROADBLOCKS FOR RPON BINDING SITES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012013621-A1 | METHODS AND USES RELATING TO THE IDENTIFICATION OF COMPOUND ASSOCIATED WITH BACTERIAL INFECTION | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |
| EP-2412819-A1 | Methods and uses relating to the identification of compound associated with bacterial infection | Sanofi-Aventis Deutschland GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| US-20110172826-A1 | Device including altered microorganisms, and methods and systems of use | SEARETE LLC | 2011-07-14 | — | — | US | disclosed |
| US-20110046195-A1 | Non-Lactone Carbocyclic and Heterocyclic Antagonists and Agonists of Bacterial Quorum Sensing | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110028945-A1 | Device including altered microorganisms, and methods and systems of use | SEARETE LLC, | 2011-02-03 | — | — | US | disclosed |
| US-20110027181-A1 | Device including altered microorganisms, and methods and systems of use | SEARETE LLC | 2011-02-03 | — | — | US | disclosed |
| WO-2007008769-A2 | USE OF PSEUDAN AND PSEUDAN INCLUSION BODIES | GEORGE MASON UNIVERSITY (US) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046195-A1 | Non-Lactone Carbocyclic and Heterocyclic Antagonists and Agonists of Bacterial Quorum Sensing | BID, HCAR1, HCAR2 | LMNA 4349/4885L3MBTL1 661/4885HTT 3194/4885 |
| US-11596626-B2 | Compound for use against pathogenic Neisseria and Haemophilus species and Moraxella catarrhalis | MLEC, MPO, B3GNT2 | LMNA 1268/4885L3MBTL1 4513/4885HTT 786/4885 |
| US-20110027181-A1 | Device including altered microorganisms, and methods and systems of use | DNASE1, MTREX, POLI | LMNA 1919/4885L3MBTL1 1345/4885HTT 1835/4885 |
| US-20210169869-A1 | Compound for Use Against Pathogenic Neisseria and Haemophilus Species and Moraxella Catarrhalis | MLEC, MPO, B3GNT2 | LMNA 1268/4885L3MBTL1 4513/4885HTT 786/4885 |
| US-10875830-B2 | Method of treatment | CFTR, MGAM, NRDC | LMNA 3042/4885L3MBTL1 2882/4885HTT 4596/4885 |
| US-20210393586-A1 | Compounds for Use in the Treatment of Bacterial Infections | BLVRB, ELANE, BPGM | LMNA 4425/4885L3MBTL1 197/4885HTT 4192/4885 |
| US-11083706-B2 | Lactams for use in the treatment of skin lesions | CUTA, MGAM, DPM1 | LMNA 2819/4885L3MBTL1 1276/4885HTT 4873/4885 |
| US-11160787-B2 | 4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one for use in the treatment of gram negative bacterial infections | PGLS, PNKP, PPIL4 | LMNA 4566/4885L3MBTL1 563/4885HTT 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.