Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL4598729 | 0.84 | KCNN4 (0.33) | RIPK1KCNN4ALDH1A1MAPTMEN1 | |
| SCHEMBL28391871 | 0.82 | KCNN4 (0.37) | RIPK1KCNN4ALDH1A1MAPTCYP17A1 | |
| Phosphonic Acid SCHEMBL11249737 | 0.81 | SMN1; SMN2 (0.35) | RIPK1KCNN4ALDH1A1MAPTKDM4E | |
| SCHEMBL25564002 | 0.70 | KCNN4 (0.40) | RIPK1KCNN4ALDH1A1MAPTKDM4E | |
| SCHEMBL15735581 | 0.69 | CYP17A1 (0.35) | RIPK1KCNN4ALDH1A1MAPTCYP17A1 | |
| SCHEMBL995627 | 0.68 | CES2 (0.39) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7714548 | 0.68 | RAB9A (0.38) | KCNN4ALDH1A1MAPTCYP17A1RAB9A | |
| SCHEMBL14827412 | 0.67 | RIPK1 (0.44) | RIPK1KCNN4MAPTKDM4ERAB9A | |
| Phosphonic Acid SCHEMBL28034212 | 0.66 | CES2 (0.50) | KCNN4ALDH1A1RAB9ANPC1 | |
| SCHEMBL995493 | 0.66 | NPC1 (0.37) | ALDH1A1MAPTRAB9ANPC1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366154-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | SANDOZ, INC. (US) | 1982-12-28 | — | — | US | disclosed |