Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867289 | 0.79 | TSHR (0.44) | RAB9ACYP19A1ACHEALDH1A1NPC1 | |
| SCHEMBL3118068 | 0.76 | MAPK1 (0.42) | KCNN4ALDH1A1MAPK1 | |
| SCHEMBL25402989 | 0.74 | KCNN4 (0.33) | RAB9AUSP2CYP19A1KCNN4SMN1; SMN2 | |
| SCHEMBL7812529 | 0.73 | RORC (0.36) | KCNN4ALDH1A1RORCNR1H2NR1H3 | |
| SCHEMBL10516000 | 0.72 | SQOR (0.35) | RAB9AUSP2SMN1; SMN2ALDH1A1CYP17A1 | |
| SCHEMBL7709329 | 0.72 | KIF11 (0.41) | RAB9AACHESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11854971 | 0.72 | KIF11 (0.41) | RAB9AACHESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9474605 | 0.71 | ESR1 (0.53) | ALDH1A1MAPK1NR1H2 | |
| SCHEMBL7714437 | 0.70 | KCNN4 (0.42) | ACHEKCNN4ALDH1A1MAPK1HDAC6 | |
| SCHEMBL7714530 | 0.70 | CA4 (0.46) | RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | claimed |
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | disclosed |