SCHEMBL306765

SCHEMBL306765

Cc1ccc(Cl)c(C(=O)O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
TP53 P04637 1/20 0.63
CSNK2A1 P68400 1/20 0.61
TDP1 Q9NUW8 4/20 0.58
CTSB P07858 1/20 0.58
LMNA P02545 2/20 0.56
POLB P06746 3/20 0.53
KDM4E B2RXH2 3/20 0.53
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
MAPT P10636 1/20 0.53
AKR1C2 P52895 2/20 0.51
AKR1C1 Q04828 2/20 0.51
CLCN2 P51788 1/20 0.51
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
L3MBTL1 Q9Y468 3/20 0.50
CASP6 P55212 2/20 0.50
CTDSP1 Q9GZU7 2/20 0.50
NSD2 O96028 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL696965 0.83 RAB9A (0.47) ALDH1A1TP53CSNK2A1TDP1CTSB
SCHEMBL1489033 0.83 RAB9A (0.47) ALDH1A1TP53CSNK2A1TDP1CTSB
SCHEMBL336771 0.83 SMN1; SMN2 (0.63) ALDH1A1CSNK2A1RAB9ANPC1AKR1C2
SCHEMBL5223645 0.81 RAB9A (0.46) ALDH1A1TP53CSNK2A1TDP1CTSB
SCHEMBL1786128 0.81 LMNA (0.50) ALDH1A1TP53CSNK2A1LMNAKDM4E
SCHEMBL787118 0.80 AKR1C2 (0.70) ALDH1A1TP53TDP1CTSBLMNA
SCHEMBL31627797 0.79 CSNK2A1 (0.68) ALDH1A1CSNK2A1POLBKDM4ECLCN2
SCHEMBL467550 0.79 CSNK2A1 (0.68) ALDH1A1CSNK2A1POLBKDM4ECLCN2
Hydrochloric Acid SCHEMBL28752341 0.79 LMNA (0.49) ALDH1A1TP53CSNK2A1LMNAKDM4E
SCHEMBL95646 0.79 TP53 (0.57) TP53LMNAPOLBKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-116396159-A Synthesis method of 2,2' -biphenyl dicarboxylic acid compound 湖南大学 2023-07-07 CN claimed
US-8373005-B2 Process for the synthesis of ethers of aromatic acids E I DU PONT DE NEMOURS AND COMPANY (US) 2013-02-12 US claimed
EP-2473469-A2 PROCESS FOR THE SYNTHESIS OF FLUORINATED ETHERS OF AROMATIC ACIDS E. I. du Pont de Nemours and Company (US) 2012-07-11 EP claimed
EP-2473468-A2 PROCESS FOR THE SYNTHESIS OF FLUORINATED ETHERS OF AROMATIC ACIDS E. I. du Pont de Nemours and Company (US) 2012-07-11 EP claimed
EP-2473470-A2 PROCESS FOR THE SYNTHESIS OF FLUORINATED ETHERS OF AROMATIC ACIDS E. I. du Pont de Nemours and Company (US) 2012-07-11 EP claimed
EP-2473471-A2 PROCESS FOR THE SYNTHESIS OF FLUORINATED ETHERS OF AROMATIC ACIDS E. I. du Pont de Nemours and Company (US) 2012-07-11 EP claimed
US-8207374-B2 Process for the synthesis of ethers of aromatic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-26 US claimed
US-7985825-B2 Process for the synthesis of ethers of aromatic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-26 US claimed
US-7943723-B2 Process for the synthesis of ethers of aromatic acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-17 US claimed
US-20100016540-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-01-21 US claimed
US-20100004422-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E.I. BU PONT DE NEMOURS AND COMPANY (US) 2010-01-07 US claimed
EP-2125687-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. Du Pont de Nemours and Company (US) 2009-12-02 EP claimed
EP-2125688-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. Du Pont de Nemours and Company (US) 2009-12-02 EP claimed
EP-2109598-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. Du Pont de Nemours and Company (US) 2009-10-21 EP claimed
EP-2109599-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. Du Pont de Nemours and Company (US) 2009-10-21 EP claimed
WO-2008082510-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-10 WO claimed
WO-2008082551-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-10 WO claimed
WO-2008079225-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-03 WO claimed
WO-2008079218-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016540-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS DDC, TYR, AHR ALDH1A1 670/4885TP53 3870/4885CSNK2A1 1022/4885
US-20100004422-A1 PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS DDC, TYR, AHR ALDH1A1 1101/4885TP53 2574/4885CSNK2A1 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.