Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440071 | 0.90 | RPS6KA2 (0.37) | MAPTRPS6KA2CNR2LMNATP53 | |
| SCHEMBL11241799 | 0.82 | CNR2 (0.36) | MAPTCNR2TP53NPSR1GHSR | |
| SCHEMBL11377390 | 0.81 | CYP3A4 (0.44) | MAPTRPS6KA2LMNATP53NPSR1 | |
| SCHEMBL11244555 | 0.81 | CNR2 (0.36) | MAPTFFAR4CNR2TP53NPSR1 | |
| SCHEMBL11235691 | 0.78 | CNR2 (0.36) | MAPTFFAR4RPS6KA2NPY5RCNR2 | |
| SCHEMBL11441222 | 0.77 | RPS6KA2 (0.40) | MAPTRPS6KA2LMNATP53CYP2C19 | |
| SCHEMBL11367236 | 0.73 | PGR (0.39) | MAPTRPS6KA2CNR2LMNATP53 | |
| SCHEMBL11364773 | 0.73 | RPS6KA2 (0.39) | MAPTRPS6KA2LMNATP53CYP2C19 | |
| SCHEMBL9184148 | 0.71 | MAPT (0.39) | MAPTRPS6KA2LMNATP53CYP2C19 | |
| SCHEMBL11375946 | 0.70 | ALOX15 (0.38) | MAPTRPS6KA2LMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |