Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 5/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244555 | 0.92 | CNR2 (0.36) | CNR2GHSRKITPDGFRAKDR | |
| SCHEMBL11235699 | 0.82 | MAPT (0.34) | CNR2GHSRTP53MAPTHTT | |
| SCHEMBL11440071 | 0.77 | RPS6KA2 (0.37) | CNR2TP53MEN1ALDH1A1MAPT | |
| SCHEMBL11241792 | 0.77 | CNR2 (0.41) | CNR2GHSRPSMB5PSMB1TP53 | |
| SCHEMBL11365556 | 0.75 | ALDH1A1 (0.37) | TP53KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL11244546 | 0.73 | CNR2 (0.41) | CNR2GHSRTP53MEN1MAPT | |
| SCHEMBL11253088 | 0.68 | TP53 (0.37) | TP53KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL11377390 | 0.68 | CYP3A4 (0.44) | TP53NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL11236725 | 0.67 | MAPT (0.39) | CNR2GHSRKITPDGFRAKDR | |
| SCHEMBL11380020 | 0.66 | CYP3A4 (0.46) | TP53MEN1NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |