Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245425 | 0.84 | TP53 (0.43) | HDAC1HDAC2HDAC6ALDH1A1KMT2A | |
| SCHEMBL9839604 | 0.78 | ALDH1A1 (0.43) | HDAC1HDAC2HDAC6ALDH1A1KMT2A | |
| SCHEMBL4886558 | 0.78 | LMNA (0.57) | HDAC1HDAC2HDAC6ALDH1A1KMT2A | |
| SCHEMBL11096840 | 0.74 | HPGD (0.53) | HDAC1HDAC2HDAC6ALDH1A1KMT2A | |
| SCHEMBL9838267 | 0.69 | KMT2A (0.49) | HDAC1HDAC2HDAC6ALDH1A1KMT2A | |
| SCHEMBL30696601 | 0.68 | KDM4E (0.47) | ALDH1A1LMNAESR1MAPTSMN1; SMN2 | |
| SCHEMBL17818709 | 0.68 | P2RX7 (0.62) | ALDH1A1HPGDP2RX7 | |
| SCHEMBL5471316 | 0.67 | HPGD (0.63) | HDAC1HDAC2HDAC6ALDH1A1KMT2A | |
| SCHEMBL5471315 | 0.67 | HPGD (0.63) | HDAC1HDAC2HDAC6ALDH1A1KMT2A | |
| SCHEMBL9097197 | 0.66 | LMNA (0.55) | HDAC1HDAC2HDAC6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |