Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886558 | 0.82 | LMNA (0.57) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL11236896 | 0.78 | HDAC1 (0.42) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL11096840 | 0.78 | HPGD (0.53) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL11245425 | 0.77 | TP53 (0.43) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL8784500 | 0.73 | LMNA (0.69) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL19203480 | 0.73 | LMNA (0.69) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL9839754 | 0.73 | LMNA (0.69) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL9838267 | 0.72 | KMT2A (0.49) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL11096886 | 0.72 | HPGD (0.56) | ALDH1A1KMT2ALMNAPOLBESR1 | |
| SCHEMBL9839633 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNAPOLBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075446-A | Synthesis of tetrahydro-2-furylated pyrimidine derivatives | KOREA ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 1991-12-24 | — | — | US | disclosed |