Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473036 | 0.80 | METAP2 (0.48) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL27781809 | 0.78 | METAP2 (0.47) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL7896700 | 0.76 | METAP2 (0.46) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL49679 | 0.76 | METAP2 (0.46) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL15856382 | 0.76 | METAP2 (0.46) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL15509351 | 0.76 | METAP2 (0.55) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL7900444 | 0.76 | METAP2 (0.46) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL21333851 | 0.76 | METAP2 (0.50) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL22652700 | 0.76 | METAP2 (0.55) | METAP2NUDT1BACE1ESR2PSMB5 | |
| SCHEMBL2799978 | 0.76 | NUDT1 (0.51) | METAP2NUDT1BACE1ESR2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339608-A | BUTANOL AND BUTANAL, COBALT, IODINE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-07-13 | — | — | US | disclosed |