SCHEMBL49679

SCHEMBL49679

Cc1cc(-c2ccccc2)c(P)c(-c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.46
NUDT1 P36639 1/20 0.43
BACE1 P56817 1/20 0.42
ESR2 Q92731 1/20 0.42
PSMB5 P28074 2/20 0.42
HDAC7 Q8WUI4 1/20 0.42
CYP2A6 P11509 1/20 0.40
CYP2B6 P20813 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.39
ALOX12 P18054 1/20 0.39
ACHE P22303 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39
HPRT1 P00492 1/20 0.38
MAOB P27338 2/20 0.38
ALDH1A1 P00352 2/20 0.38
AKT1 P31749 1/20 0.38
AKT2 P31751 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4473036 0.80 METAP2 (0.48) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL27781809 0.78 METAP2 (0.47) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL7896700 0.76 METAP2 (0.46) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL22652700 0.76 METAP2 (0.55) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL2528210 0.76 BACE1 (0.54) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL7900444 0.76 METAP2 (0.46) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL15509351 0.76 METAP2 (0.55) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL21333851 0.76 METAP2 (0.50) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL2799978 0.76 NUDT1 (0.51) METAP2NUDT1BACE1ESR2PSMB5
SCHEMBL11237644 0.76 METAP2 (0.46) METAP2NUDT1BACE1ESR2PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119069796-A Electrolyte, electrode assembly, battery and electricity utilization device 宁德时代新能源科技股份有限公司 2024-12-03 CN claimed
CN-113149882-B Gem-difluoroolefin-pyrroline compound and preparation method and application thereof 西南医科大学 2023-04-07 CN claimed
CN-113149882-A Gem-difluoroolefin-pyrroline compound and preparation method and application thereof 西南医科大学 2021-07-23 CN claimed
US-6936672-B2 Mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-30 US claimed
EP-0174174-B1 A METHOD OF STABILISING HYDROXY-CONTAINING POLYMERS OF BUTADIENE OR SUBSTITUTED DERIVATIVES THEREOF ELF ATOCHEM S.A. (FR) 1990-05-23 EP claimed
US-4593128-A Using a di- or triphenylphosphine compound ATLANTIC RICHFIELD COMPANY (US) 1986-06-03 US claimed
EP-0174174-A2 A method of stabilising hydroxy-containing polymers of butadiene or substituted derivatives thereof ELF ATOCHEM S.A. (FR) 1986-03-12 EP claimed
CN-119069796-A Electrolyte, electrode assembly, battery and electricity utilization device 宁德时代新能源科技股份有限公司 2024-12-03 CN disclosed
US-20240217907-A1 PHENOL MIXTURE, EPOXY RESIN, EPOXY RESIN COMPOSITION, CURED PRODUCT, AND ELECTRICAL/ELECTRONIC COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2024-07-04 US disclosed
CN-112566893-B Preparation of diesters of (meth) acrylic acid from epoxides 赢创运营有限公司 2024-03-01 CN disclosed
CN-113149882-B Gem-difluoroolefin-pyrroline compound and preparation method and application thereof 西南医科大学 2023-04-07 CN disclosed
CN-113149882-A Gem-difluoroolefin-pyrroline compound and preparation method and application thereof 西南医科大学 2021-07-23 CN disclosed
EP-2963094-B1 SOFT MAGNETIC THERMOSETTING ADHESIVE FILM, SOFT MAGNETIC FILM-LAMINATED CIRCUIT BOARD, AND POSITION-DETECTING DEVICE NITTO DENKO CORP (JP) 2021-06-23 EP disclosed
WO-2011089985-A1 COSMETIC COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2011-07-28 WO disclosed
US-20110151336-A1 LITHIUM BATTERY SAMSUNG SDI CO., LTD. (KR) 2011-06-23 US disclosed
US-20090062460-A1 CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE HITACHI CHEMICAL CO., LTD. (JP) 2009-03-05 US disclosed
US-20080262135-A1 REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-10-23 US disclosed
EP-0174174-B1 A METHOD OF STABILISING HYDROXY-CONTAINING POLYMERS OF BUTADIENE OR SUBSTITUTED DERIVATIVES THEREOF ELF ATOCHEM S.A. (FR) 1990-05-23 EP disclosed
US-4593128-A Using a di- or triphenylphosphine compound ATLANTIC RICHFIELD COMPANY (US) 1986-06-03 US disclosed
EP-0174174-A2 A method of stabilising hydroxy-containing polymers of butadiene or substituted derivatives thereof ELF ATOCHEM S.A. (FR) 1986-03-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062460-A1 CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE NCAPH, RAD51, H1-2 METAP2 4224/4885NUDT1 1242/4885BACE1 3265/4885
US-20240217907-A1 PHENOL MIXTURE, EPOXY RESIN, EPOXY RESIN COMPOSITION, CURED PRODUCT, AND ELECTRICAL/ELECTRONIC COMPONENT ESR1, EED, PTGES METAP2 2777/4885NUDT1 1740/4885BACE1 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.