Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898334 | 0.86 | NISCH (0.41) | NISCHACHE | |
| SCHEMBL11240137 | 0.82 | ITGB3 (0.42) | NISCH | |
| SCHEMBL5153906 | 0.79 | LMNA (0.33) | — | |
| Bromide SCHEMBL11367894 | 0.77 | IDO1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL11352198 | 0.77 | IDO1 (0.37) | — | |
| SCHEMBL5154750 | 0.75 | TDP1 (0.41) | — | |
| Bromide SCHEMBL11354189 | 0.74 | ACHE (0.39) | ACHE | |
| Hydrochloric Acid SCHEMBL10884932 | 0.74 | TDP1 (0.39) | — | |
| SCHEMBL3782607 | 0.72 | HPGD (0.42) | NISCHACHE | |
| SCHEMBL13196361 | 0.72 | DAPK3 (0.38) | DAPK3NTRK1PIM1FLT3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012822-B1 | 3,4-DISUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR THEIR PRODUCTION | C.H. BOEHRINGER SOHN (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0012822-A1 | 3,4-Disubstituted 2-phenylimino-imidazolidines, their acid addition salts, pharmaceutical preparations containing them and process for their production | C.H. BOEHRINGER SOHN (DE) | 1980-07-09 | — | — | EP | disclosed |