Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 10/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238439 | 0.82 | DAPK3 (0.36) | NISCH | |
| SCHEMBL5153906 | 0.79 | LMNA (0.33) | MAPT | |
| Hydrochloric Acid SCHEMBL11352198 | 0.77 | IDO1 (0.37) | IDO1TDO2EGFR | |
| Bromide SCHEMBL11354245 | 0.77 | PTGS1 (0.41) | CYP2D6MEN1ALDH1A1MAPTHTT | |
| Bromide SCHEMBL11367894 | 0.77 | IDO1 (0.37) | IDO1TDO2EGFR | |
| SCHEMBL5898334 | 0.75 | NISCH (0.41) | NISCHMEN1ALDH1A1MAPTHTT | |
| SCHEMBL13131511 | 0.72 | IDO1 (0.50) | ITGB3ITGAVNISCHIDO1MAOB | |
| SCHEMBL11229542 | 0.72 | ALDH1A1 (0.47) | IDO1TDO2CYP2D6MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10877604 | 0.70 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL1491361 | 0.69 | ITGB3 (0.50) | ITGB3ITGAVIDO1MAOBTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012822-B1 | 3,4-DISUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR THEIR PRODUCTION | C.H. BOEHRINGER SOHN (DE) | 1982-12-01 | — | — | EP | disclosed |
| EP-0012822-A1 | 3,4-Disubstituted 2-phenylimino-imidazolidines, their acid addition salts, pharmaceutical preparations containing them and process for their production | C.H. BOEHRINGER SOHN (DE) | 1980-07-09 | — | — | EP | disclosed |