Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231975 | 0.85 | HTR1D (0.48) | FFAR1PTGESFFAR4 | |
| SCHEMBL1787452 | 0.79 | CYP3A4 (0.54) | — | |
| SCHEMBL11245815 | 0.78 | TP53 (0.43) | PPARGCFDAKT1TP53MDM2 | |
| SCHEMBL8174800 | 0.78 | CETP (0.54) | FFAR1PTGESMMEACECPA1 | |
| SCHEMBL27627503 | 0.74 | AKT1 (0.46) | CFDAKT1 | |
| SCHEMBL11345408 | 0.74 | FFAR1 (0.56) | FFAR1PTGESMMEACECPA1 | |
| SCHEMBL9538055 | 0.73 | TAAR1 (0.56) | FFAR1PTGESMMEACECPA1 | |
| SCHEMBL27316147 | 0.72 | ALOX15 (0.53) | PPARGCFDTP53 | |
| SCHEMBL10680144 | 0.72 | ALOX15 (0.62) | CFD | |
| SCHEMBL13133127 | 0.72 | PARP1 (0.47) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| US-4256754-A | PHENYL-1,2,4-TRIAZOLE DERIVATIVE, CARBAMATE | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |