Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.53 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680144 | 0.87 | ALOX15 (0.62) | ALOX15GABRA1GABRB2CFDGAA | |
| SCHEMBL10684531 | 0.86 | ALOX15 (0.65) | ALOX15ALOX12TUBB1KDM4EMEN1 | |
| SCHEMBL28289539 | 0.86 | ALOX15 (0.63) | ALOX15ALOX12TUBB1GABRA1GABRB2 | |
| SCHEMBL9244145 | 0.84 | ALOX15 (0.48) | ALOX15GABRA1GABRB2CFDESR1 | |
| SCHEMBL22064390 | 0.83 | LDHA (0.58) | ALOX15ALOX12ALDH1A1NR3C1FOS | |
| SCHEMBL17254145 | 0.81 | CYP4F2 (0.63) | ALOX15ALOX12TUBB1CFDGAA | |
| SCHEMBL11657273 | 0.81 | ALOX15 (0.47) | ALOX15ALOX12TUBB1CFDGAA | |
| SCHEMBL27627503 | 0.80 | AKT1 (0.46) | ALOX15GABRA1GABRB2CFDALDH1A1 | |
| SCHEMBL20095259 | 0.80 | CFD (0.49) | ALOX15ALOX12TUBB1CFDGAA | |
| SCHEMBL19663053 | 0.80 | CFD (0.53) | ALOX15ALOX12TUBB1CFDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030701-C | Indole derivatives and process for production thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-01-17 | — | — | CN | disclosed |
| CN-1056685-A | Indole derivatives and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |