Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680144 | 0.83 | ALOX15 (0.62) | ALOX15GABRA1GABRB2CFDALDH1A1 | |
| SCHEMBL27316147 | 0.80 | ALOX15 (0.53) | ALOX15GABRA1GABRB2CFDALDH1A1 | |
| SCHEMBL9244145 | 0.80 | ALOX15 (0.48) | ALOX15GABRA1GABRB2CFDALOX5AP | |
| SCHEMBL22064390 | 0.79 | LDHA (0.58) | ALOX15ALDH1A1PTGS1 | |
| SCHEMBL27561746 | 0.76 | TRPV1 (0.53) | AKT1ALOX5 | |
| SCHEMBL11841548 | 0.76 | ALOX15 (0.63) | AKT1ALOX15GABRA1GABRB2ALOX5 | |
| SCHEMBL163415 | 0.76 | GABRA1 (0.51) | ALOX15GABRA1GABRB2ALOX5PTGS1 | |
| SCHEMBL28787058 | 0.75 | CFD (0.47) | AKT1CFDALDH1A1PTGS1 | |
| SCHEMBL27611659 | 0.75 | CYP4F2 (0.44) | AKT1CFDALDH1A1ALOX5CYP4F2 | |
| SCHEMBL11238516 | 0.74 | FFAR1 (0.45) | AKT1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100562511-C | 2-aryl-acetic acids, their derivative and contain their pharmaceutical composition | DOMPE SPA (IT) | 2009-11-25 | — | — | CN | claimed |
| CN-1768026-A | 2-aryl-acetic acids, their derivatives and pharmaceutical compositions containing them | DOMPE SPA (IT) | 2006-05-03 | — | — | CN | claimed |
| CN-100562511-C | 2-aryl-acetic acids, their derivative and contain their pharmaceutical composition | DOMPE SPA (IT) | 2009-11-25 | — | — | CN | disclosed |
| CN-1768026-A | 2-aryl-acetic acids, their derivatives and pharmaceutical compositions containing them | DOMPE SPA (IT) | 2006-05-03 | — | — | CN | disclosed |