Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238516 | 0.78 | FFAR1 (0.45) | TP53MDM2PPARGAKT1CFD | |
| SCHEMBL15977315 | 0.76 | IDH1 (0.49) | IDH1GABRA1GABRB2MAPK1 | |
| SCHEMBL11245819 | 0.73 | TP53 (0.38) | TP53MDM2BCL2L1MCL1SLC7A5 | |
| SCHEMBL27627503 | 0.72 | AKT1 (0.46) | AKT1CFDALOX5APGABRA1GABRB2 | |
| SCHEMBL11351998 | 0.72 | PTGS1 (0.51) | PPARGIDH1LMNA | |
| SCHEMBL9164207 | 0.72 | AKT1 (0.55) | TP53MDM2PPARGBCL2L1MCL1 | |
| SCHEMBL4512063 | 0.71 | ALOX5 (0.50) | AKT1CFDMAPTMAPK1PTPN1 | |
| SCHEMBL9558386 | 0.71 | L3MBTL1 (0.41) | TP53MDM2PPARGBCL2L1MCL1 | |
| SCHEMBL10680144 | 0.70 | ALOX15 (0.62) | CFDGABRA1GABRB2ALOX15LMNA | |
| SCHEMBL27512435 | 0.69 | MTNR1B (0.57) | MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | disclosed |
| US-4256754-A | PHENYL-1,2,4-TRIAZOLE DERIVATIVE, CARBAMATE | BASF AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |