Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248482 | 0.84 | MEN1 (0.47) | AMY1APLAUMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11243699 | 0.81 | SIRT5 (0.41) | AMY1APLAUMEN1KMT2A | |
| SCHEMBL3613054 | 0.81 | RAB9A (0.47) | MEN1KMT2AHTTHDAC3HDAC1 | |
| Bromide SCHEMBL11240412 | 0.80 | RAB9A (0.46) | MEN1KMT2AHTTHDAC3HDAC1 | |
| SCHEMBL3612676 | 0.79 | CSNK2A1 (0.45) | AMY1APLAUMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3604799 | 0.77 | ALOX5 (0.61) | AMY1AHSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2393684 | 0.76 | HDAC3 (0.59) | HSD17B10MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL3612827 | 0.75 | ATP4A (0.47) | PLAUMEN1KMT2ASMN1; SMN2TYR | |
| Bromide SCHEMBL7141567 | 0.75 | HDAC3 (0.58) | HSD17B10MEN1KMT2ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11254127 | 0.75 | HDAC3 (0.60) | HSD17B10MEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003640-B1 | ANTISECRETORY GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-01-27 | — | — | EP | disclosed |