Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11238849 | 0.68 | LMNA (0.43) | HTR1AAPOBEC3AHTTAPOBEC3GMEN1 | |
| SCHEMBL11586250 | 0.67 | THRA (0.41) | HTR1AMEN1GAAKMT2A | |
| Bromide SCHEMBL11170592 | 0.67 | MAOB (0.43) | KMT2A | |
| SCHEMBL22609079 | 0.65 | GNAI3 (0.49) | GNAI3GNAO1GNAI1 | |
| Water SCHEMBL21084713 | 0.63 | GNAI3 (0.47) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13567371 | 0.63 | GNAI3 (0.44) | GNAI3GNAO1GNAI1APOBEC3AAPOBEC3G | |
| SCHEMBL5541916 | 0.63 | HRH3 (0.44) | HTR1AMEN1KMT2A | |
| Bromide SCHEMBL1534056 | 0.62 | BBOX1 (0.50) | GNAI3GNAO1GNAI1APOBEC3AAPOBEC3G | |
| SCHEMBL5541909 | 0.62 | HTR1A (0.35) | HTR1AMEN1KMT2A | |
| SCHEMBL11586422 | 0.61 | KMT2A (0.46) | HTR1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350518-A | Plant growth regulating substituted alkylammonium salts | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |