Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64274 | 0.84 | TDP1 (0.52) | TSHRCYP2C19TDP1L3MBTL1POLB | |
| SCHEMBL9825190 | 0.83 | ALDH1A1 (0.48) | TSHRCYP2C19TDP1L3MBTL1POLB | |
| SCHEMBL5574638 | 0.83 | TSHR (0.52) | TSHRCYP2C19TDP1L3MBTL1POLB | |
| SCHEMBL28259085 | 0.82 | LMNA (0.43) | CYP3A4MAPTBLMPMP22CES2 | |
| SCHEMBL28866465 | 0.82 | PARP10 (0.41) | TSHRCYP2C19TDP1L3MBTL1POLB | |
| SCHEMBL6267389 | 0.81 | TSHR (0.50) | TSHRCYP2C19TDP1L3MBTL1POLB | |
| SCHEMBL11322544 | 0.80 | TDP1 (0.48) | TSHRCYP2C19TDP1L3MBTL1POLB | |
| SCHEMBL2146344 | 0.80 | TDP1 (0.48) | TSHRCYP2C19TDP1L3MBTL1POLB | |
| SCHEMBL28257506 | 0.80 | CES2 (0.45) | ALDH1A1CES2CES1RAB9ASMN1; SMN2 | |
| Potassium Ion SCHEMBL9820487 | 0.80 | ALDH1A1 (0.40) | TSHRCYP2C19TDP1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339382-A | Process for manufacturing N-arylthiocarbamoyl-2-amino-1H-isoindole-1,3-(2H)diones | GULF OIL CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| US-4339382-A | Process for manufacturing N-arylthiocarbamoyl-2-amino-1H-isoindole-1,3-(2H)diones | GULF OIL CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0016571-A1 | N-(Arylthiocarbamoyl)-2-amino-1H-isoindole-1,3-(2H)diones, processes for their preparation and their use as plant growth regulators | Gulf Oil Corporation (US) | 1980-10-01 | — | — | EP | disclosed |