Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.80 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.80 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GNA15 | P30679 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244569 | 0.88 | FFAR1 (0.76) | FFAR1FFAR4RXFP1GNA15PTGER3 | |
| SCHEMBL11240957 | 0.87 | FFAR1 (0.67) | FFAR1FFAR4RXFP1TDP1HDAC1 | |
| SCHEMBL11249779 | 0.85 | FFAR1 (0.71) | FFAR1FFAR4GNA15PTGER3TDP1 | |
| SCHEMBL1509 | 0.84 | TAAR1 (0.57) | FFAR1FFAR4HDAC1HDAC8 | |
| SCHEMBL11233308 | 0.80 | FFAR1 (0.65) | FFAR1FFAR4RXFP1TDP1HDAC1 | |
| SCHEMBL11235397 | 0.79 | FFAR1 (0.70) | FFAR1FFAR4RXFP1TDP1HDAC1 | |
| SCHEMBL11236732 | 0.77 | FFAR1 (0.61) | FFAR1FFAR4RXFP1TDP1HDAC1 | |
| SCHEMBL9238416 | 0.77 | FFAR1 (0.61) | FFAR1FFAR4RXFP1TDP1HDAC1 | |
| SCHEMBL14924230 | 0.77 | FFAR1 (0.82) | FFAR1FFAR4GNA15PTGER3TDP1 | |
| SCHEMBL11246781 | 0.77 | FFAR1 (0.60) | FFAR1FFAR4HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |