Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768634 | 0.89 | MAPT (0.52) | L3MBTL1MAPTGAAPKMKMT2A | |
| SCHEMBL11768640 | 0.89 | MAPT (0.52) | L3MBTL1MAPTGAAPKMKMT2A | |
| SCHEMBL8962795 | 0.82 | L3MBTL1 (0.49) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8962801 | 0.82 | L3MBTL1 (0.49) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL6945061 | 0.82 | L3MBTL1 (0.62) | L3MBTL1MAPTGAAPKMALDH1A1 | |
| SCHEMBL6945066 | 0.82 | L3MBTL1 (0.62) | L3MBTL1MAPTGAAPKMALDH1A1 | |
| SCHEMBL497336 | 0.81 | MME (0.56) | PSMB5ALDH1A1NPSR1 | |
| SCHEMBL73955 | 0.81 | MME (0.56) | PSMB5ALDH1A1NPSR1 | |
| SCHEMBL11581853 | 0.81 | MME (0.56) | PSMB5ALDH1A1NPSR1 | |
| SCHEMBL4677601 | 0.79 | TDP1 (0.50) | L3MBTL1MAPTGAAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067641-A2 | Amino acids | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| EP-0067641-A2 | Amino acids | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |