Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962795 | 1.00 | L3MBTL1 (0.49) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL6945061 | 0.84 | L3MBTL1 (0.62) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL6945066 | 0.84 | L3MBTL1 (0.62) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL11241002 | 0.82 | L3MBTL1 (0.61) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL4677601 | 0.82 | TDP1 (0.50) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL2252337 | 0.80 | POLB (0.48) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL29860289 | 0.79 | TLR2 (0.46) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL27624443 | 0.79 | TLR2 (0.46) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL1356510 | 0.78 | ALDH1A1 (0.54) | L3MBTL1TDP1POLBAPEX1CTDSP1 | |
| SCHEMBL1356508 | 0.78 | ALDH1A1 (0.54) | L3MBTL1TDP1POLBAPEX1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578470-A | USING CYSTEINE | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST (NL) | 1996-11-26 | — | — | US | disclosed |