Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680394 | 0.87 | POLB (0.47) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL2252337 | 0.83 | POLB (0.48) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL6945066 | 0.82 | L3MBTL1 (0.62) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL6945061 | 0.82 | L3MBTL1 (0.62) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL8962801 | 0.82 | L3MBTL1 (0.49) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL8962795 | 0.82 | L3MBTL1 (0.49) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL27624443 | 0.82 | TLR2 (0.46) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL29860289 | 0.82 | TLR2 (0.46) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL11241002 | 0.79 | L3MBTL1 (0.61) | TDP1L3MBTL1POLBAPEX1CTDSP1 | |
| SCHEMBL1356508 | 0.78 | ALDH1A1 (0.54) | TDP1L3MBTL1POLBAPEX1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945448-B1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-6020496-A | 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |