Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RRM1 | P23921 | 1/20 | 0.53 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239525 | 0.89 | RAB9A (0.86) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL7239062 | 0.89 | RAB9A (1.00) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL7240198 | 0.83 | RAB9A (0.80) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL7228332 | 0.83 | RAB9A (0.80) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL7231423 | 0.83 | RAB9A (0.80) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL7230092 | 0.83 | RAB9A (0.80) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL7238318 | 0.83 | RAB9A (0.80) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL7239776 | 0.83 | RAB9A (0.80) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL5099990 | 0.82 | RAB9A (0.76) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 | |
| SCHEMBL5094470 | 0.82 | RAB9A (0.76) | RAB9ANPC1GSTO1CSNK2A1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | claimed |
| US-7365094-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2008-04-29 | — | — | US | claimed |
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | 4SC AG (DE) | 2007-02-01 | — | — | US | claimed |
| CN-1732163-A | Aromatic compounds as anti-inflammatory and immunomodulatory and antiproliferative agents | 4 SC AG (DE) | 2006-02-08 | — | — | CN | claimed |
| EP-1581478-A1 | DHODH-INHIBITORS AND METHOD FOR THEIR IDENTIFICATION | 4SC AG (DE) | 2005-10-05 | — | — | EP | claimed |
| EP-1578741-A1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2005-09-28 | — | — | EP | claimed |
| US-20040192758-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2004-09-30 | — | — | US | claimed |
| WO-2004056747-A1 | DHODH-INHIBITORS AND METHOD FOR THEIR IDENTIFICATION | 4SC AG (DE) | 2004-07-08 | — | — | WO | claimed |
| WO-2004056797-A1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-07-08 | — | — | WO | claimed |
| CN-1732163-B | Aromatic compounds as anti-inflammatory and immunomodulatory and antiproliferative agents | 4SC AG | 2012-07-18 | — | — | CN | disclosed |
| EP-1578741-B1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |
| EP-2283898-A1 | Aromatic compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2011-02-16 | — | — | EP | disclosed |
| US-7365094-B2 | Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2008-04-29 | — | — | US | disclosed |
| CN-1732163-A | Aromatic compounds as anti-inflammatory and immunomodulatory and antiproliferative agents | 4 SC AG (DE) | 2006-02-08 | — | — | CN | disclosed |
| US-20040192758-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | 4SC AG (DE) | 2004-09-30 | — | — | US | disclosed |
| US-20030055263-A1 | Carboxylic acid derivatives, medicaments comprising these compounds, their use and processes for their production | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027193-A1 | Method of identifying inhibitors of DHODH | DHODH, SQOR, NDUFA5 | RAB9A 2708/4885NPC1 2985/4885GSTO1 349/4885 |
| US-20030055263-A1 | Carboxylic acid derivatives, medicaments comprising these compounds, their use and processes for their production | TERT, POT1, REV1 | RAB9A 3964/4885NPC1 2716/4885GSTO1 1600/4885 |
| US-20040192758-A1 | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | PPARG, PPARD, PPARA | RAB9A 3873/4885NPC1 1509/4885GSTO1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.