Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11608199 | 0.82 | LMNA (0.46) | LMNAALDH3A1TP53NOD1GAA | |
| SCHEMBL1272442 | 0.78 | ACLY (0.48) | LMNAALDH3A1TP53NOD1GAA | |
| SCHEMBL15910233 | 0.78 | HTR6 (0.47) | LMNAALDH3A1TP53GAAALDH1A1 | |
| SCHEMBL30661141 | 0.78 | HTR6 (0.47) | LMNAALDH3A1TP53GAAALDH1A1 | |
| SCHEMBL23560964 | 0.76 | ALDH3A1 (0.56) | LMNAALDH3A1NOD1GAACXCL8 | |
| SCHEMBL22670414 | 0.75 | LMNA (0.46) | LMNAALDH3A1TP53NOD1GAA | |
| SCHEMBL15074499 | 0.72 | HTT (0.66) | LMNAALDH3A1TP53NOD1GAA | |
| SCHEMBL8545209 | 0.72 | HTR6 (0.53) | LMNAALDH3A1TP53NOD1GAA | |
| SCHEMBL1272465 | 0.72 | OPRD1 (0.45) | LMNAALDH3A1TP53GAA | |
| SCHEMBL6958148 | 0.72 | MCL1 (0.55) | LMNATP53NOD1NOD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123291-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |