Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245155 | 0.90 | MEN1 (0.49) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11246999 | 0.85 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Diflubenzuron SCHEMBL18837607 | 0.82 | RAB9A (0.59) | MEN1KMT2ANPC1RAB9AMAPT | |
| Diflubenzuron SCHEMBL42416 | 0.82 | RAB9A (0.59) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10712873 | 0.82 | RAB9A (0.47) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11247284 | 0.82 | PCTP (0.55) | KMT2ANPC1RAB9ACA1CA2 | |
| SCHEMBL7605796 | 0.81 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL11246141 | 0.81 | ATM (0.46) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10708913 | 0.81 | FFAR2 (0.55) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9324631 | 0.80 | RAB9A (0.57) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |